The aim of present study was to compare the effects of yoga therapy versus effect of aerobic exercise on climacteric symptoms, perceived stress and quality of life in Perimenopausal women. Sixty symptomatic women between 40-55 years of age were divided into 2 groups: (A) Yoga group and (B) Aerobic Exercise group. Yoga group performed yoga asanas 5 times a week for 6 weeks, while Aerobic Exercise group walked 5 times a week for 6 weeks. Greene Climacteric Scale (GCS), Perceived Stress Scale (PSS) and MENQOL questionnaire were assessed at the baseline and after 6 weeks of intervention. Statistical analysis revealed that both Yoga and Aerobic Exercise group showed significant improvement in Greene Climacteric Scale (GCS), Perceived Stress Scale (PSS) and MENQOL questionnaire (p Ë‚ 0.05) post 6 weeks of intervention. However, Yoga exercises showed comparatively significant improvement with (p Ë‚ 0.05) in climacteric symptoms, perceived stress and quality of life than aerobic exercise. This study concluded that 6 weeks of Yoga exercises showed comparatively significant improvement in climacteric symptoms, perceived stress and quality of life than aerobic exercise in Perimenopausal women aged from 40-55 years.