The purpose of the study was to find out the effect of specific drill training package on selected physiological variables namely resting pulse rate and breath holding time among college men football players. To achieve the said purpose, thirty men football players were selected at random from Government Boy’s Degree College Baramulla of Jammu and Kashmir State, India as subjects. The selected subjects were divided into two equal groups of fifteen subjects each. The group I underwent specific drill training package for four days per week for twelve weeks. Group II acted as control group who did not participate any special training programmes apart from their regular routine, as per their curriculum. The following variables namely resting pulse rate and breath holding time were selected as criterion variables. All the subjects of two groups were tested on selected dependent variables at prior to and immediately after the training programme. The analysis of covariance (ANCOVA) was used to analyze the significant difference, if any between the groups. The .05 level of confidence was fixed as the level of significance to test the “F” ratio obtained by the analysis of covariance, which was considered as an appropriate. The results of the study revealed that there was a significant difference between specific drill training package group and control group on selected physiological variables namely resting pulse rate and breath holding time.